Tackling high-burden for patients and under-researched medical conditions

Proposals under topic HORIZON-HLTH-2025-01-DISEASE-07 should aim to deliver results that are directed, tailored towards and contributing to most of the following expected outcomes:

• The scientific and clinical communities make effective use of state-of-the-art information, data, technologies, tools and best practices to better understand the condition underpinning the development of diagnostics, therapeutics and/or preventive strategies.
• The scientific and clinical community exchange data, knowledge and best practices, thereby strengthening their collaboration and building knowledge and care networks in Europe and beyond.
• The scientific and clinical community make wide use of newly established and where relevant open access databases and/or integrate them with existing infrastructures for storage and sharing of collected data according to FAIR principles, thereby encouraging further use of the data.
• Policymakers and funders are informed of the research advances made and consider further support in light of the sustainability of the studies.
• Patients and caregivers are constructively engaged with the research, which also caters for their needs.
• Health professionals have access to and use improved clinical guidelines on diagnosis and/or treatment of the condition.

A number of medical conditions fail to be recognised and/or be correctly diagnosed in a significant proportion of patients. As a consequence, they are inadequately treated and often can become a chronic and high burden for the patient. These medical conditions, including:

1. myalgic encephalomyelitis/chronic fatigue syndrome,
2. autism,
3. gynaecological diseases,
4. low back pain,
5. other,

may be insufficiently researched even though they manifest with high prevalence. Applicants should explicitly state in their proposal which of the above medical conditions is targeted and the proposed work should address only this specific medical condition. Please note that the following medical conditions are not in the scope of this topic: rare diseases, including rare cancers, and under-research medical conditions already addressed by projects funded under topic HORIZON-HLTH-2024-DISEASE-03-14-two-stage.

Interested parties can find more information and apply on the Funding and Tenders Portal.